Laboklin Uk

+++ New Test in Rough and Smooth Collie +++
We are pleased to announce that, in cooperation with professor Leeb of the University of Bern in Switzerland, Laboklin is now able to offer DNA testing for Inflammatory Pulmonary Disease (IPD). Sample requirements consist of Buccal Swabs or 0.5-1ml whole blood in an EDTA Blood Tube.
Inflammatory Pulmonary Disease (IPD) is an inherited lung disease affecting the Collie breed and characterised by recurrent pneumonia, clinical symptom...s were seen when affected puppies were only few days old and include foamy vomiting, shallow breathing, cough, increased breathing sounds and fever. Affected dogs responded to therapy with antibiotics and secretolytics, but tended to relapse quickly without antibiotic treatment.
For more information, please visit: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
See More

+++ New DNA Bundle Available in Soft Coated Wheaten Terrier +++
We are pleased to announce that Laboklin can now offer a DNA bundle package in the Soft Coated Wheaten Terrier breed.
The new bundle will include testing for Degenerative Myelopathy (DM Exon 2), Protein Losing Nephropathy (PLN), Paroxysmal Dyskinesia (PxD), Microphthalmia (RBP4), and Hyperuricosuria (HUU) – all for a reduced cost of £156 (including VAT).
... Sample requirements consist of Buccal Swabs or whole blood in an EDTA blood tube. Turnaround time is 1-2 weeks.
For more information, please visit: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
See More

+++ New Test Available in Giant Schnauzer +++
We are pleased to announce that Laboklin can now offer DNA testing for NECAP-1 Progressive Retinal Atrophy in Giant Schnauzer. Sample requirements for this test consist of Buccal Swabs or 0.5-1ml of whole blood in an EDTA blood tube.
NECAP-1 Progressive Retinal Atrophy (NECAP-1 PRA) is a novel form of PRA implicating the Giant Schnauzer breed. The disease is caused by a mutation in the NECAP1 gene. Like other forms of PRA this d...isease leads to retinal degeneration and subsequent blindness. The variant was identified by scientists at the Animal Health Trust and it is thought to be autosomal recessive.
For more information, please visit: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp….
See More

+++ van den Ende-Gupta Syndrome (VDEGS) in Fox Terrier +++
We are pleased to announce that DNA testing for van den Ende-Gupta Syndrome (VDEGS) in Fox Terrier breeds has now been optimised. Results for this test can now be expected within 1 week (previously 2-3 weeks). Sample requirements consist of Buccal Swabs or 0.5-1ml whole blood in an EDTA blood tube.
Van den Ende-Gupta Syndrome is characterized by symptoms similar to those found in craniomandibular osteopathy (CMO). All... affected dogs exhibit a prominent underbite with short maxilla. Additionally, bones are often not mineralized and luxation of the elbow or patella as well as swollen knee joints can be found regularly.
For more information, please visit: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
See More

+++ Raine Syndrome in Border Collie +++
We are pleased to announce that DNA testing for Raine Syndrome has now been optimised. Results for this test can now be expected within 1 week (previously 2-3 weeks). Sample requirements consist of Buccal Swabs or 0.5-1ml whole blood in an EDTA blood tube.
Raine Syndrome is characterised by symptoms similar to those found in craniomandibular osteopathy (CMO). Affected dogs exhibit severe tooth wear resulting in pulpitis and the removal... of most teeth. These symptoms result by hypo-mineralisation of the teeth and weakened enamel. Skeletal bones can also be found to be less mineralised in these dogs.
For more information, please visit: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
See More

+++ PCD in Alaskan Malamute +++
We are pleased to announce that Laboklin can now offer DNA testing for Primary Ciliary Dyskinesia (PCD) in the Alaskan Malamute breed. Sample requirements consist of Buccal Swabs or 0.5-1ml whole blood in an EDTA blood tube.
Primary ciliary dyskinesia (PCD) is an autosomal-recessive genetic disease characterized by recurrent infections of the respiratory tract as well as reduced male fertility. Around 50% of the affected dogs develop situs inv...ersus (Kartagener syndrome). The underlying cause is a motility defect in the respiratory cilia responsible for airway clearance and in the flagella responsible for propelling sperm cells.
Please note, we would not yet have much information as to the prevalence of this disease in Alaskan Malamutes in the UK. However, we can confirm we have tested a dog which was showing symptoms, and this returned an affected result.
For more information, please visit: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
See More

+++ New Colour Test Available +++
We are pleased to announce that Laboklin can now offer DNA testing for the I Locus (phaeomelanin intensity). Sample requirements consist of Buccal Swabs or 0.5-1ml whole blood in an EDTA blood tube.
I-Locus controls the intensity of the red pigment (phaeomelanin). Phaeomelanin is the tan pigment including all shades of red, gold, fawn, sable and cream pigments. The richness of the red colour varies in the different breeds, from the very rich... red of the Irish setter to cream.
The genetic variant is relevant for all breeds with brighter colours and has already been found in some breeds such as Australian Shepherd, Eurasier, Husky, Alaskan Malamute, French Bulldog and Pug.
For more information, please visit: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
See More

+++ Update +++
We are pleased to announce that the S Locus (piebald) test is now performed in-house and as such the cost of this test has been reduced to £48.
Turnaround time is now 1-2 weeks; previously this has been 4-5 weeks.
... Sample requirements remain to consist of Buccal Swabs or 0.5-1ml whole blood in an EDTA blood tube.
For more information, please feel free to visit: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp….
See More

+++ New Test Available in Labrador Retriever +++
We are pleased to announce that Laboklin can now offer DNA testing for Stargardt disease (STGD) in the Labrador Retriever breed. Sample requirements consist of Buccal Swabs or 0.5-1ml whole blood in an EDTA blood tube.
Stargardt disease is an inherited retinal degenerative disease that leads to visual impairment and blindness. Photoreceptors are light-sensing cells found in the retina of the eye. There are two types of photore...ceptors: rods and cones. In Stargardt disease both cones and rods degenerate, but for unclear reasons, cones are more strongly affected in most cases. The mutation responsible for Stargardt disease in Labrador retriever has been identified by researchers at The Swedish University of Agricultural Sciences, it is a mutation in the ABCA4 gene.
More information on this test can be found at: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
If you have previously had your dog tested with us, this test can be ordered on the stored DNA. For this all we would require is the previous sample ID of the dog in question. For more information on this, please do not hesitate to contact us.
See More

+++ New Test Available in Schnauzer +++
We are pleased to announce that Laboklin can now offer DNA Testing for Dilated Cardiomyopathy (DCM) in the Schnauzer breed. Sample requirements consist of Buccal Swabs or 0.5-1ml whole blood in an EDTA Blood tube.
Dilated Cardiomyopathy is an inherited disease affecting the Standard Schnauzer breed. The disease is characterised by a swelling of one of the heart’s ventricles (lower chambers). Affected dogs may not exhibit any signs for y...ears, however, eventually, start exhibiting symptoms of ill health including: Lethargy, loss of appetite, coughing especially during exercise, gasping for breath, fainting or collapsing and progressive abdominal swelling. Although these signs can signify the onset of heart failure, they are also shared with other conditions and therefore testing is vital for the diagnosis.
This test is also a part of the Kennel Club DNA Testing Scheme with Laboklin for this breed.
For more information, please feel free to visit our website at: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp….
See More

+++ New Kennel Club DNA Testing Scheme +++
We are pleased to announce that Leukoencephalomyelopathy (LEMP) and Leonberger Polyneuropathy 2 (LPN2) are now part of the Kennel Club Testing Scheme with Laboklin for the Leonberger breed.
A reminder that all results which are to be submitted to the Kennel Club must include 2 forms of identification. This can be in the form of a Kennel Club Registration name/number, as well as a microchip or tattoo number.

+++ update +++
The Lafora test is now valid for:
- Chihuahua... - French Bull Dog , - Welsh Corgi (both Cardigan and Pembroke)
In addition to Basset and Miniature Wirehaired Dachshund
Lafora disease (LD) / Myoclonic Epilepsy is a late onset inherited neurological disorder affecting a number of breeds including Beagle and Miniature Wirehaired Dachshund ( MWHD ).
Symptoms starts after the age of 5 years and include a characteristic quick and involuntary jerking of the head backward ( myoclonus ), which can occur spontaneously or triggered by noise, light flashing or flickering, jaw smacking, panic attacks, impaired vision, aggression and urinary incontinence. High pitched vocalisations have been seen in affected dogs. Symptoms can progress to epilepsy and seizures.
The disease is caused by a mutation which causes intracellular accumulation of abnormal glycogen (Lafora bodies). Age of onset: after 5 years of ages.
At the moment we only accept blood in EDTA blood tubes for this test. We cannot accept swabs at this time.
http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
See More

+++ New Test Available in Bull Terrier and Miniature Bull Terrier +++
We are pleased to announce that Laboklin can now offer DNA testing for Laryngeal Paralysis in Bull Terrier and Miniature Bull Terrier breeds. Sample requirements consist of Buccal Swabs or 0.5-1ml whole blood in an EDTA Blood tube.
Laryngeal paralysis is an inherited disease affecting Bull Terriers and characterised by difficulties in breathing, especially during physical activity, and may cause death by s...uffocation in severe cases. Clinical signs include decreasing exercise tolerance, progressive laryngeal stridor, voice impairment, episodes of breathing difficulties and collapsing. In the Bull Terrier and Miniature Bull Terrier, a genetic variant has been identified as a major genetic risk factor for an early onset form of laryngeal paralysis.
For more information, please feel free to visit our website at: http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp….
See More

+++ LABOKLIN at Crufts 2019 +++
10 % DISCOUNT
We are pleased to inform you that LABOKLIN will be at Crufts 2019 from 7th to 10th March and we look forward to seeing you there.
... Our stand is located in Hall 3 opposite the restaurant, it is stand number 3-7a.
10% Discount on all DNA tests submitted at Crufts ! and this includes our Breed DNA Bundles.
Instructions, forms, newsletter and more details can be found on the Laboklin Crufts web page:
http://www.laboklin.co.uk/laboklin/dispat cher.jsp?id=Crufts
See More

+++ new test +++
Mycobacterium Avium Complex ( MAC ) sensitivity in Miniature Schnauzer.
We are very pleased to announce that the MAC test is at last available at our lab. Sample required is either a buccal swab or EDTA blood. Of course you can also order the test on stored DNA.
... The MAC mutation has been found to be associated with a genetic predisposition to infection with systemic avian tuberculosis in Miniature Schnauzers.
http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
See More

+++ Chondrodystrophy (CDDY with IVDD Risk) and Chondrodysplasia (CDPA) +++
N E W
The test checks for two mutations: CDDY with IVDD Risk, and CDPA.
... Chondrodystrophy CDDY (FGF4-18) which causes short legs and the risk of developing Intervertebral Disc Disease (IVDD).
Chondrodysplasia CDPA (FGF4-12), which causes the short legged phenotype in a number of breeds.
Chondrodystrophy (CDDY with IVDD Risk) is a trait that is common to many dog breeds and it is characterised by shorter legs due to shorter long bones. CDDY can also be associated with Intervertebral Disc Disease (IVDD) due to premature degeneration of the intervertbral disc. The intervertebral disc lie between the vertebrae and it is made of a cartilage which separate vertebrae from each other, absorb shocks and allow slight movement of the vertebrae. In affected dogs, premature calcification of part of the disc at early age (from birth to 1 year of age) results in degeneration of all discs in young dogs. These abnormal discs are susceptible to herniation into the spinal canal where the inflammation, and hemorrhage can cause severe pain and neurological dysfunction. CDDY is inherited as a semi-dominant trait which means that dogs with 2 copies of the mutation are smaller than dogs with only 1 copy. As for IVDD, the inheritance follows a dominant mode, meaning that 1 copy of CDDY mutation is sufficient to predispose dogs to IVDD.
The CDDY mutation has been found in breeds such as: Basset Hound, Beagle, Bichon Frise, Cardigan Welsh Corgi, Cavalier King Charles Spaniel, Chesapeake Bay Retriever, Chihuahua, American Cocker Spaniel, Coton de Tulear, Dachshund, Dandie Dinmont Terrier, English Springer Spaniel, French Bulldog, Havanese, Jack Russell Terrier, Nova Scotia Duck Tolling Retriever, Pekingese, Pembroke Welsh Corgi, Poodle (Miniature and Toy), Portuguese Water Dog, Scottish Terrier, Shih Tzu.
The second mutation CDPA explains the short-legged phenotype known as chondrodysplasia (CDPA) in breeds such as Basset Hound, Pembroke Welsh Corgi, Dachshunds, West Highland White Terriers and Scottish Terriers. CDPA inheritance is considered to follow am autosomal dominant mode.
In some breeds both mutations are present and so breeders will be able to plan breeding to reduce occurrence of CDDY, while retaining the short-legged phenotype CDPA.
http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
See More

+++new KC Official DNA testing Scheme+++
Sensory Neuropathy ( SN ) in Border Collie is now part of the KC official DNA testing scheme in Border Collie.
Sensory Neuropathy (SN) is an inherited neurological disease affecting the Border Collie breed. The disease is characterised by degeneration of sensory and motor nerve cells. Symptoms begin between the age of 2 and 7 months and include: knuckling of the feet, wounds caused by self chewing or licking of the limbs due to lack of... feeling, progressive loss of coordination (ataxia), progressive loss of sensation occurs in all limbs, urinary incontinence and regurgitation can occur in the later stages of the disease. Affected dogs are usually euthanized around the age of 2 years.
http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…
See More

+++ Laboklin Lafora DNA test is now accepted by the Kennel Club +++
We are pleased to announce that our Lafora DNA test is now part of the Kennel Club DNA testing scheme with Laboklin in Beagle and Miniature Wirehaired Dachshund.
http://www.laboklin.co.uk/laboklin/showGe neticTest.jsp…