Malaria Consortium

About Malaria Consortium

Established in 2003, Malaria Consortium is one of the world’s leading non-profits. Our mission is to improve lives in Africa and Asia through sustainable, evidence-based programmes that combat targeted diseases and promote child and maternal health.

Reviews

User

We're marking our 4th year of providing preventive #malaria treatments to children under 5 in the #Sahel region to protect them during the rainy season
Seasonal malaria chemoprevention (#SMC) has been found to reduce cases by as much as 89% 📉
More: http://bit.ly/2JVuu10

User

'Effective altruism' is a new teammate in the fight to #endMalaria
Through GiveWell, our seasonal malaria chemoprevention programme is top-rated for its effectiveness, providing donors with confidence in their donation
Read more: https://buff.ly/2uvlgnk

User

How can 'edutainment' help us to #endMalaria?
In #Mozambique, primary school children take part in interactive sessions to acquire basic knowledge on #malaria transmission, signs and symptoms, malaria prevention methods and the importance of timely care seeking.
Learn more: https://buff.ly/2Ju8crf

User

Today marks the start of our #MCFridayReads series - every Friday, we bring you a new perspective from our work across Africa and Asia on sustainable, evidence-based programmes that combat targeted diseases and promote child health
The first perspective comes from South Sudan, where community-based primary healthcare is having a significant positive impact.
Read more:

User

Antibiotic resistance is a growing global threat. Our new study in Bangladesh is testing a new community-based approach to fighting it
Read more: https://buff.ly/2J2PQdb

User

The rainy season in the Sahel is fast approaching. To protect children and infants under the age of five caregivers should ensure their child receives seasonal malaria chemoprevention (SMC). Through the ACCESS-SMC project, 10,000 deaths and 10 million cases of malaria have been averted with SMC. We will ensure that children protected in 2017 receive SMC again 2018, but to keep up the momentum in reducing child mortality and malaria, more investments needs to be made if countries are to reach universal coverage of SMC.
Learn more: https://www.malariaconsortium.org/…/SMC %20at%20scale-%20sav…

User

Did you miss us at MIM 2018 in Dakar, Senegal last month?
Catch up with this update in MalariaWorld 👇

User

How can better communications be used to help #endMalaria?
In #Ethiopia, we've run a project in communities and schools with the aim of improving people's use of community based health services.
We developed tailored behaviour change communications such as danger signs tools and educational films which were rolled out to communities in the Boloso Sore and Halaba districts
... Learn more: http://bit.ly/ICIMSbrief
See More

User

A data revolution in Africa could reinvigorate efforts to beat #malaria. But what does this mean?
Learn more: http://bit.ly/Datarevolution

User

It's #WorldMalariaDay!
We need to accelerate efforts to beat malaria by 2030 - but Data collection in the countries with the heaviest malaria burden is still weak. Let's set a data revolution in Africa in motion by beginning with three steps:
- 1: Invest in malaria surveillance systems... - 2: Improve the quality of data collected - 3: Strengthen the capacity of staff to collect, analyze, and utilize data to beat malaria!
Read more in this opinion piece in Devex from our Technical Director, Dr James Tibenderana
http://bit.ly/2r0z3zA
See More

User

TODAY is World Malaria Day
Every two minutes, #malaria kills a child under 5. To beat the disease, we must get smarter about how we fight it - targeting what works best, where it is needed most. For this we need a data revolution in Africa
Read more ➡️ https://t.co/E8iHOHEXDW

User

Global malaria progress has stalled, therefore we are calling upon Commonwealth leaders to halve malaria in @commonwealth2018 by 2023. Malaria is both preventable and treatable, but we can’t beat it without the backing from #ourCommonwealth. Share to stand with us and show you’re #ReadyToBeatMalaria #MalariaMustDie

User

As the Malaria Summit begins and Commonwealth leaders make ambitious commitments to fight malaria, Baroness Sheehan, Liberal Democrat Spokesperson for International Development, calls for a data revolution in Africa to support a smarter approach to defeating the disease.
A smarter approach means being able to target what works best where it is needed most; it means being more cost-effective and having greater impact; and it means driving progress and saving more lives.
To a...chieve this, we must invest in surveillance systems, improve the quality of malaria data, train staff to collect, analyse and use data, and scale up innovative digital solutions to support malaria.
https://bit.ly/2JVzK6i
#ReadyToBeatMalaria #MalariaMustDie #ourCommonwealth #CHOGM
See More

User

Every two minutes a child dies from malaria, which is both preventable and treatable. This week, we have the power to change this.
With 90% of people living in #ourCommonwealth countries at risk, we’re calling on Commonwealth leaders at the Commonwealth Heads of Government Meeting 2018 to get #ReadyToBeatMalaria. #MalariaMustDie

User

Today at #MIM2018:
Our presentations continue throughout the day at the 7th Multilateral Initiative on Malaria Conference in Dakar, Senegal.
We will be LIVE from 1pm with our next Q&A with our Technical Director, Dr James Tibenderana plus guests Professor Brian Greenwood and Professor Fred Binka to discuss drugs and vaccines.
... Our symposium on ACCESS-SMC: scaling up seasonal malaria chemoprevention in the Sahel: final results, lessons learned and long-term outlook is taking place in Tent B from 9am.
For more information about our presence at MIM, click here: bit.ly/MCatMIM
See More

User

We're live from #MIM2018! Our Technical Director, Dr James Tibenderana in discussion with Dr Marcel Turner

User

People in Kibuuba village, #Uganda, respect Moses. He is not only their community health worker, but also an all-round health provider.
#WHWWeek #HealthForAll #WorldHealthDay USAID - US Agency for International Development DFID - UK Department for International Development Malaria Must Die

User

Health worker Joseph not only bikes for health, he also plays a crucial role in bringing progress to Kyarujumba village in #Uganda. We are sharing his story for World Health Worker Week!
#HealthWorkersCount #WHWWeek
USAID - US Agency for International Development DFID - UK Department for International Development Malaria Must Die

User

It's World Health Worker Week!
We trained village health team workers like Stella, below, in diagnosis & hospital referrals for #malaria in #Uganda. This ensures children in remote communities are still able to receive prompt treatment for malaria.
#HealthWorkersCount #WHWWeek

User

حاربو الباعوض للقضا على الملاريا

User

There is aracket of recruitment firms in Kampala which claim to give pipo jobs at this org yet not they seem to WK with reception and HR

User

Melhorar o salario, ou melhor pagar em dollar

User

Malaria Consortium is very good, because project always supported to National program and help to provided health education

User

A malaria parasite within a human red blood cell. The large circle in the parasite is a food vacuole. Stacked heme are visible inside the vacuole.



Researchers at the University of Washington have discovered a method of treating malaria with magnetic fields that could prove revolutionary in controlling the disease the World Health Organization calls one of the world’s most complex and serious human health concerns.



Henry Lai, UW research professor of bioengineering, says the malaria parasite Plasmodium appears to lose vigor and can die when exposed to oscillating magnetic fields, which Lai thinks may cause tiny iron-containing particles inside the parasite to move in ways that damage the organism.



“If further studies confirm our findings and their application in animals and people, this would be an inexpensive and simple way to treat a disease that affects 500 million people every year, almost all in third-world countries,” Lai said. According to the World Health Organization, as many as 2.7 million people die of malaria every year. Approximately 1 million of those are children.



In the past two decades, the emergence of drug-resistant malaria parasites has created enormous problems in controlling the disease. Lai says his method could bypass those concerns because it is unlikely Plasmodium could develop a resistance to magnetic fields.



Malaria is spread by female Anopheles mosquitoes. The organism first invades the liver, then re-emerges into the bloodstream and attacks red blood cells. This is what causes malaria’s hallmark symptoms: fever, uncontrolled shivering, aches in the joints and headaches. Infected blood cells can block blood vessels to the brain, causing seizures and death. Other vital organs are also at risk.



Lai’s research appears to take advantage of how the parasites feed. Malaria parasites “eat” the hemoglobin in red blood cells of the host. They break down the globin portion of the hemoglobin molecule, but the iron portion, or the heme, is left intact because the parasite lacks the enzyme needed to degrade it. This causes a problem for the parasite because free heme molecules can cause a chain reaction of oxidation of unsaturated fatty acids, leading to membrane damage in the parasite. The malaria organism renders the free heme molecules non-toxic by binding them into long stacks – like “tiny bar magnets,” according to Lai.



He and three other researchers have exposed Plasmodium falciparum, the deadliest of the four malaria parasite species, to a weak alternating, or oscillating, magnetic field. Data sets showed that exposed samples ended up with 33 to 70 percent fewer parasites than unexposed samples. Measurements of hypoxanthine, a precursor for nucleic acid synthesis used by the parasite, indicated that metabolic activities had also significantly slowed in exposed samples. Such reductions would be enough to manage malaria, Lai said.



The oscillating magnetic field may affect the parasites in two ways, according to Lai. In organisms still in the process of binding free heme molecules into stacks, the alternating field likely “shakes” the stacked heme molecules, preventing further stacking. That would allow harmful heme free reign within the parasite. If the parasite is further along in its life cycle and has already bound the heme into stacks, the oscillating field could cause the stacks to spin, causing damage and death of the parasite.



Although initially promising, Lai says more research is needed.



“We need to make certain that it won’t harm the host,” Lai said. “My guess is that it won’t. It’s a very weak magnetic field, just a little stronger than the earth’s. The difference is that it is oscillating.”



If the method is proven effective and safe, Lai envisions rooms equipped with magnetic coils to produce the oscillating field.



“It would be very easy. People could come to the room and sit and read or whatever while they’re being treated,” he said. “Or you could set it up in the back of a big transport truck, then drive from village to village to treat people.”



Collaborating researchers include Jean E. Feagin, UW associate professor of pathobiology and senior scientist at the Seattle Biomedical Research Institute; and Ceon Ramon, UW electrical engineering research scientist.

User

حاربو الباعوض للقضا على الملاريا

User

There is aracket of recruitment firms in Kampala which claim to give pipo jobs at this org yet not they seem to WK with reception and HR

User

Melhorar o salario, ou melhor pagar em dollar

User

Malaria Consortium is very good, because project always supported to National program and help to provided health education

User

A malaria parasite within a human red blood cell. The large circle in the parasite is a food vacuole. Stacked heme are visible inside the vacuole.



Researchers at the University of Washington have discovered a method of treating malaria with magnetic fields that could prove revolutionary in controlling the disease the World Health Organization calls one of the world’s most complex and serious human health concerns.



Henry Lai, UW research professor of bioengineering, says the malaria parasite Plasmodium appears to lose vigor and can die when exposed to oscillating magnetic fields, which Lai thinks may cause tiny iron-containing particles inside the parasite to move in ways that damage the organism.



“If further studies confirm our findings and their application in animals and people, this would be an inexpensive and simple way to treat a disease that affects 500 million people every year, almost all in third-world countries,” Lai said. According to the World Health Organization, as many as 2.7 million people die of malaria every year. Approximately 1 million of those are children.



In the past two decades, the emergence of drug-resistant malaria parasites has created enormous problems in controlling the disease. Lai says his method could bypass those concerns because it is unlikely Plasmodium could develop a resistance to magnetic fields.



Malaria is spread by female Anopheles mosquitoes. The organism first invades the liver, then re-emerges into the bloodstream and attacks red blood cells. This is what causes malaria’s hallmark symptoms: fever, uncontrolled shivering, aches in the joints and headaches. Infected blood cells can block blood vessels to the brain, causing seizures and death. Other vital organs are also at risk.



Lai’s research appears to take advantage of how the parasites feed. Malaria parasites “eat” the hemoglobin in red blood cells of the host. They break down the globin portion of the hemoglobin molecule, but the iron portion, or the heme, is left intact because the parasite lacks the enzyme needed to degrade it. This causes a problem for the parasite because free heme molecules can cause a chain reaction of oxidation of unsaturated fatty acids, leading to membrane damage in the parasite. The malaria organism renders the free heme molecules non-toxic by binding them into long stacks – like “tiny bar magnets,” according to Lai.



He and three other researchers have exposed Plasmodium falciparum, the deadliest of the four malaria parasite species, to a weak alternating, or oscillating, magnetic field. Data sets showed that exposed samples ended up with 33 to 70 percent fewer parasites than unexposed samples. Measurements of hypoxanthine, a precursor for nucleic acid synthesis used by the parasite, indicated that metabolic activities had also significantly slowed in exposed samples. Such reductions would be enough to manage malaria, Lai said.



The oscillating magnetic field may affect the parasites in two ways, according to Lai. In organisms still in the process of binding free heme molecules into stacks, the alternating field likely “shakes” the stacked heme molecules, preventing further stacking. That would allow harmful heme free reign within the parasite. If the parasite is further along in its life cycle and has already bound the heme into stacks, the oscillating field could cause the stacks to spin, causing damage and death of the parasite.



Although initially promising, Lai says more research is needed.



“We need to make certain that it won’t harm the host,” Lai said. “My guess is that it won’t. It’s a very weak magnetic field, just a little stronger than the earth’s. The difference is that it is oscillating.”



If the method is proven effective and safe, Lai envisions rooms equipped with magnetic coils to produce the oscillating field.



“It would be very easy. People could come to the room and sit and read or whatever while they’re being treated,” he said. “Or you could set it up in the back of a big transport truck, then drive from village to village to treat people.”



Collaborating researchers include Jean E. Feagin, UW associate professor of pathobiology and senior scientist at the Seattle Biomedical Research Institute; and Ceon Ramon, UW electrical engineering research scientist.

More about Malaria Consortium

Malaria Consortium is located at 244-254 Cambridge Heath Road, E2 9DA London, United Kingdom
+44 (0)20 35596431
http://www.malariaconsortium.org http://www.youtube.com/malariaconsortiumuk http://twitter.com/FightingMalaria