Cnelm

https://www.nature.com/articles/s41598-01 8-36674-9 Recent research on fasting suggests that it increases metabolic activity and reduces ageing damage. Four volunteers were fasted for 58 hours and their blood tested at intervals. Researchers saw an increase in the citric acid (energy) cycle as well as increases in purine and pyrimidine - indicating increased protein synthesis, gene expression and antioxidant status. The blood samples also showed increased levels of metabolites which usually decline as we age and a general increase in other metabolites. The researchers hypothesise that the increased antioxidants are in response to the oxidative state of starvation and say further research into this mechanism is warranted.

https://www.nature.com/articles/s41538-01 8-0030-8 Researchers have found that nanoparticles in foods may bind to and alter the life cycle and behaviour of gut bacteria. They noted that this may exert a beneficial or a negative effect, depending on the altered behaviour. Silica nanoparticles seemed to inhibit infections such as H. pylori, but may also increase inflammation by making it harder for the immune system to sense pathogenic bacteria.

https://www.physiology.org/…/abs/10.115 2/ajprenal.00487.2018 New research suggests that high blood pressure may be exacerbated by a zinc deficiency. Mice who were zinc deficient developed hypertension until they were supplemented with zinc, whereby their blood pressure returned to normal. The animals' blood pressure also returned to normal when given a drug which inhibits sodium chloride cotransporter (NCC), which regulates blood pressure via sodium absorption. The research suggests that NCC activity increases when zinc levels are low and that zinc may therefore be an important nutrient for managing hypertension.

https://www.nature.com/articles/s41598-01 8-36890-3 Recent research suggests that two common emulsifiers commonly found in many foods impact negatively on gut bacteria and anxiety levels. Mice who were given these emulsifiers daily over 12 weeks showed an increase in anxiety (for male mice) and a decrease in social behaviours (in female mice). Gut bacteria was affected in both sets of mice and there was also an increase in systemic and gut inflammation, which has been shown to affect the brain via the vagus nerve

https://www.physiology.org/d…/abs/10.11 52/ajpregu.00351.2018 New research suggests that trying to hydrate after exercise with soft drinks could further dehydrate and place strain on the kidneys. Participants who consumed a fructose-containing soft drink after exercise had increased levels of plasma creatinine, mild dehydration and increased blood pressure compared to controls who had consumed only water.

https://pubs.acs.org/doi/abs/10.1021/acs. jafc.8b05888 Recent research suggests that bone broth may have cardioprotective properties. Peptides released during the cooking process seem to block enzymes related to heart disease and these peptides had been sufficiently reduced during the cooking process as to be able to pass through the gut wall ad therefore exert an effect.

https://www.medicalnewstoday.com/articles /324207.php… New research suggests that circadian rhythms may be the key to intermittent fasting's positive health benefits. The research which looked at how fasting influences circadian rhythms in the liver and skeletal muscles, showed that fasting mice used less oxygen and energy. The researchers noted that fasting influenced the circadian rhythm and cellular responses and that skeletal muscle was more responsive to fasting than the liver. They hypothesise that fasting enables a variety of cellular responses to reprogramme, positively affecting cellular functions, benefiting health and protecting against age-associated diseases.

https://www.sciencedirect.com/‚Ķ/artic‚Ä ¶/pii/S0735109718391861 A new study backs up previous research that length and quality of sleep impact on cardiovascular health. The researchers analysed the medical data of 3,974 individuals and looked at the prevalence and rate of progression of vascular problems not yet clinically relevant. Participants who slept under 6 hours every night had a 27% increase in the risk for atherosclerosis, compared to those who slept between 7 and 8 hours each night. Poor sleep quality (waking regularly) was associated with a 34% increase in atherosclerosis risk. Researchers point out that quality seems more important than quantity however.

https://www.nature.com/articles/s41467-01 8-07859-7 A new study suggests that pomegranates and berries could help maintain the integrity of the gut barrier, thus reducing the incidence of IBD. The research found that a compound formed from the interaction of polyphenols in pomegranates, berries and gut bacteria may reduce inflammation and tighten gut cell junctions. In people who lack the specific gut bacteria necessary for this interaction, the benefits may not be seen.

https://www.nature.com/articles/s41380-01 8-0322-z New research suggests that a maternal diet with sufficient choline may reduce the development of Alzheimer's disease in their offspring. Mice with a genetic predisposition to develop the disease developed fewer disease-associated brain changes where their mothers had been supplemented with the nutrient compared with non-supplemented mice. In addition, they found that the protective effect of maternal choline supplementation pe...rsisted across multiple generations, even though the descendants' diets were not enriched with choline. The researchers believe that the methyl-donor choline exerts these effects by its action of converting homocystiene to methionine, thus avoiding build up of homocysteine in the brain. Choline also appeared to reduce activity of hyperactive microglia cells in the brain.
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https://www.thelancet.com/…/PIIS0140-67 36(18)31809…/fulltext A new meta analysis has studied at how much fibre we need to prevent chronic disease and premature mortality in order to develop better guidelines. The research found that people who consume the most fibre are 15–30% less likely to die prematurely from chronic disease, compared with those who eat the least fibre. The study suggests that eating more than 29g per day yields the most health benefits, which equates to roughly 10 portions of fruits and vegetables per day. The study cautions against getting fibre from too many whole grains, as these can deplete iron in some.

https://www.pnas.org/content/116/1/217#T1 Research has found that inorganic nitrate from green leafy vegetables might help protect against non-alcoholic fatty liver disease (NAFLD), in mice at least. When mice were supplemented a high-fat, high-sugar Western diet with nitrate, their weight and fat mass gain, blood sugar and liver fat levels were significantly lower than those who had not been supplemented. Researchers hypothesise that this is due to the anti-oxidative and increased cell metabolism effects of nitrate.

https://academic.oup.com/…/article-abst …/108/6/1249/5239886… Recent research suggests that optimal levels of magnesium may play an important role in vitamin D levels. Previous research from the same scientists showed that magnesium deficiency inhibits vitamin D synthesis and the metabolism pathway, with this study looking at whether increased magnesium status would impact on vitamin D levels. This research suggested that magnesium supplementation increased vitamin D levels in people who had low levels initially, but it reduced levels in those with initially high levels, thereby adjusting levels as needed, which may be necessary in order to avoid potentially toxic plasma levels.

https://www.cell.com/immuni…/fulltext/S 1074-7613(18)30526-0… New research into the role of vitamin A suggests that it may mediate the relationship between gut bacteria and the immune system. The presence of vitamin A in the gut seems to prevent the immune system from becoming overactive, thereby allowing bacteria to reside there. Scientists found that gut bacteria adjust the amount of active vitamin A in both the gut and the liver, which was shown to regulate the host immune response. Some pathogenic bacteria may also work to lower levels of the protein needed to activate vitamin A.

https://onlinelibrary.wiley.com/doi/full/ 10.1002/oby.22287 New research suggests that a personalised approach to obesity is necessary after researchers found four sub-types. The research looked at data from 2,458 participants who had undergone bariatric surgery and identified four different groups of people with differing metabolic profiles - diabetic, disordered eating behaviours, average obesity-consistent profiles but low levels of disordered eating and people who had been obese since childhood. Some groups responded better to surgery whilst others lost weight more effectively pre-surgery. Researchers believe that by correctly identifying the sub-type, better outcomes may be possible.

https://www.cell.com/immuni…/fulltext/S 1074-7613(18)30478-3… Recent research suggests that Lactobacillus rhamnosus increases bone mass in mice at least. Mice were given the probiotic over a period of 4 weeks, during which time it stimulated butyrate production. Butyrate increases production of Treg cells both within the gut and the bone marrow, which in turn stimulates the production of Wnt10b protein - necessary for osteoblastic activity and bone growth. Further research looking at the effects in humans is warranted.

https://agingdefeated.com/remember-that-b it-about-early-to…/ New research suggests that people who go to sleep later and wake later are at a higher risk of death. Data was gathered from 433,268 men and women aged between 38 and 73 and in the 9% of participants who described themselves as 'definite' evening types (latest sleepers and risers) there was a 10% increased risk of death compared to definite morning types. This was strongest in older participants but there was no increased risk of death in 'moderate' evening types. Researchers also found an increased risk of psychological disorders, diabetes, neurological disorders, gastrointestinal disorders and respiratory disorders in late sleepers. Researchers hypothesise that this is in part due to disruption of the natural circadian rhythm if eating or sleeping too late.

https://abstractsonline.com/pp8/#!/4649/p resentation/32057 New research suggests that gut bacteria may also inhabit brain cells. The researchers found bacteria - mainly Firmicutes, Proteobacteria, and Bacteroidetes - in the brains of all 34 brains they studied - whether healthy or affected by neurological disease - except for germ-free mice's brains, which were sterile just the same as their guts. The research did not reveal the mechanisms via which the bacteria entered the brain and could see no damaging effects from their presence. Future research could examine how this proposed “brain microbiome” could maintain or threaten the health of the brain.

https://www.medicalnewstoday.com/articles /323478.php… Recent research into the effects of probiotics suggest that they may be harmful in the case of increased gut permeability. When the gut membrane becomes permeable, this leads to inflammation. The researchers found that where the gut lining is compromised, the introduction of probiotics may be harmful as they break through the barrier, which may lead to increased inflammation. Further research in this area is warranted.

I'm studying the Nutrition Science BSc + Nutritional Therapy Practice Diploma (NTPD). I'm loving the science focus and feel I'll be in a good position to disseminate research and continue m learning when I qualify. Plus, the NLP tools I've learnt as a part of the NTPD have already benefited me personally and I feel they will be hugely beneficial in my future NT practice.

I started studying at CNELM in 2014 with foundation Chemistry and Biology, to obtain entry to the Nutrition Science degree. At 33 I am following my passion to become a nutritional therapist and I couldn't think of a better place to study it! The staff are always so friendly and accommodating, you're able to do distance learning which means you can watch lectures as and when you can. Every lecture is riveting and there are such a wide range of lecturers you really get exposed to the best in the field!

CNELM is truly passionate and committed to nutritional education, and they deserve all the immense respect they have achieved over the years.

I'm studying the Nutrition Science BSc + Nutritional Therapy Practice Diploma (NTPD). I'm loving the science focus and feel I'll be in a good position to disseminate research and continue m learning when I qualify. Plus, the NLP tools I've learnt as a part of the NTPD have already benefited me personally and I feel they will be hugely beneficial in my future NT practice.

I started studying at CNELM in 2014 with foundation Chemistry and Biology, to obtain entry to the Nutrition Science degree. At 33 I am following my passion to become a nutritional therapist and I couldn't think of a better place to study it! The staff are always so friendly and accommodating, you're able to do distance learning which means you can watch lectures as and when you can. Every lecture is riveting and there are such a wide range of lecturers you really get exposed to the best in the field!

CNELM is truly passionate and committed to nutritional education, and they deserve all the immense respect they have achieved over the years.